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Vitamin B complex: how much to take

A B complex combines several B vitamins in one pill. Amounts vary a lot between brands, and B6 is the one to watch.

Calculator Official intake Study doses Best form Safety Sources

Adults 18+ only
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Official daily intake

Values per B vitamin for adults (your row is highlighted after you set your profile):

Thiamin (B1)

EFSA (European Food Safety Authority)

PRI (population reference intake)

Safe upper limit: not set

No safe limit set (not enough data).

EFSA sets thiamin per energy eaten (0.1 mg per MJ), so there is no single daily number.

Source: EFSA 2017 · EFSA 2025

NIH / NASEM (United States)

RDA (recommended dietary allowance)

Men1.2 mg
Women1.1 mg
Pregnancy1.4 mg
Breastfeeding1.4 mg

Safe upper limit: not set

No safe limit set.

Source: National Academies (NASEM) 2019

Riboflavin (B2)

EFSA (European Food Safety Authority)

PRI (population reference intake)

Men1.6 mg
Women1.6 mg
Pregnancy1.9 mg
Breastfeeding2 mg

Safe upper limit: not set

No safe limit set (not enough data).

Source: EFSA 2017 · EFSA 2025

NIH / NASEM (United States)

RDA (recommended dietary allowance)

Men1.3 mg
Women1.1 mg
Pregnancy1.4 mg
Breastfeeding1.6 mg

Safe upper limit: not set

No safe limit set.

Source: National Academies (NASEM) 2019

Niacin (B3)

EFSA (European Food Safety Authority)

PRI (population reference intake)

Safe upper limit: not set

EFSA safe limit depends on the form: 10 mg for nicotinic acid, 900 mg for nicotinamide. Pick the form below.

EFSA sets niacin per energy eaten (1.6 mg NE per MJ), so there is no single daily number.

Source: EFSA 2017 · EFSA 2025

NIH / NASEM (United States)

RDA (recommended dietary allowance)

Men16 mg
Women14 mg
Pregnancy18 mg
Breastfeeding17 mg

Safe upper limit: 35 mg a day

Safe limit applies to niacin from supplements and fortified foods (flushing).

Source: National Academies (NASEM) 2019

Pantothenic acid (B5)

EFSA (European Food Safety Authority)

AI (adequate intake)

Men5 mg
Women5 mg
Pregnancy5 mg
Breastfeeding7 mg

Safe upper limit: not set

No safe limit set (not enough data).

Source: EFSA 2017 · EFSA 2025

NIH / NASEM (United States)

AI (adequate intake)

Men5 mg
Women5 mg
Pregnancy6 mg
Breastfeeding7 mg

Safe upper limit: not set

No safe limit set.

Source: National Academies (NASEM) 2019

Vitamin B6

EFSA (European Food Safety Authority)

PRI (population reference intake)

Men1.7 mg
Women1.6 mg
Pregnancy1.8 mg
Breastfeeding1.7 mg

Safe upper limit: 12 mg a day

EFSA lowered the B6 safe limit to 12 mg in 2023 (nerve damage at high long-term intakes).

Source: EFSA 2017 · EFSA 2025

NIH / NASEM (United States)

RDA (recommended dietary allowance)

Men 18-501.3 mg
Men 51+1.7 mg
Women 18-501.3 mg
Women 51+1.5 mg
Pregnancy1.9 mg
Breastfeeding2 mg

Safe upper limit: 100 mg a day

Source: National Academies (NASEM) 2019

Biotin (B7)

EFSA (European Food Safety Authority)

AI (adequate intake)

Men40 µg
Women40 µg
Pregnancy40 µg
Breastfeeding45 µg

Safe upper limit: not set

No safe limit set (not enough data).

Source: EFSA 2017 · EFSA 2025

NIH / NASEM (United States)

AI (adequate intake)

Men30 µg
Women30 µg
Pregnancy30 µg
Breastfeeding35 µg

Safe upper limit: not set

No safe limit set.

Source: National Academies (NASEM) 2019

Folate (B9)

EFSA (European Food Safety Authority)

PRI (population reference intake)

Men330 µg
Women330 µg
Pregnancy600 µg
Breastfeeding500 µg

Safe upper limit: 1,000 µg a day

Safe limit is for folic acid and methylfolate from supplements and fortified foods, counted as plain µg (not DFE).

Source: EFSA 2017 · EFSA 2025

NIH / NASEM (United States)

RDA (recommended dietary allowance)

Men400 µg
Women400 µg
Pregnancy600 µg
Breastfeeding500 µg

Safe upper limit: 1,000 µg a day

Safe limit is for synthetic folic acid, counted as plain µg (not DFE).

NIH advises women who could become pregnant to take 400 µg folic acid a day from supplements or fortified food.

Source: National Academies (NASEM) 2019

Targets are in µg DFE (dietary folate equivalents). 1 µg folic acid taken with food counts as about 1.7 µg DFE.

Vitamin B12

EFSA (European Food Safety Authority)

AI (adequate intake)

Men4 µg
Women4 µg
Pregnancy4.5 µg
Breastfeeding5 µg

Safe upper limit: not set

No adverse effects defined, so no safe limit.

Source: EFSA 2017 · EFSA 2025

NIH / NASEM (United States)

RDA (recommended dietary allowance)

Men2.4 µg
Women2.4 µg
Pregnancy2.6 µg
Breastfeeding2.8 µg

Safe upper limit: not set

No safe limit set.

Over 50, NIH advises getting B12 mainly from fortified food or a supplement (absorption from food drops).

Source: National Academies (NASEM) 2019

Doses used in studies

These are doses tested in research, not personal advice. Some exceed the upper limit because they were short courses or given under medical care.

B complex is checked per vitamin. Enter each amount from your label.

Best form and why

No best form

Why: Pick a B complex with vitamin B6 at or below 12 mg (the EFSA safe limit) and folic acid at 400 µg or less. Doses of 50 to 100 mg of each B vitamin are rarely needed.

EFSA 2025

Food sources

Whole grains, meat, eggs, dairy, legumes, leafy greens.

Interactions

See the single-vitamin pages: biotin affects lab tests, folic acid can mask B12 deficiency.

Safety

Many "B-50" and "B-100" products contain 50 to 100 mg B6, several times the EFSA safe limit of 12 mg.

Pregnant, breastfeeding, on medication, or managing a health condition? Check with a doctor or pharmacist before starting a supplement.

Sources

  1. Official reference EFSA (2017). Dietary Reference Values for nutrients: Summary report. EFSA Supporting Publications
  2. Official reference EFSA (2025). Overview on Tolerable Upper Intake Levels as derived by the SCF and the EFSA NDA Panel (version 11, August 2025). EFSA
  3. Official reference National Academies (NASEM) (2019). Dietary Reference Intakes: RDA, AI and UL tables (via NIH ODS Nutrient Recommendations). Food and Nutrition Board

Values checked: November 12, 2026.

Fact sheets on other sites

Independent summaries to read alongside this page. PillMath is not affiliated with these sites.

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