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Creatine: how much to take

Creatine raises the energy store in muscle and is one of the best-studied sports supplements. Most research uses creatine monohydrate.

Calculator Official intake Study doses Best form Safety Sources

Adults 18+ only
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Official daily intake

Creatine is not an essential nutrient, so there is no official daily intake. Only study doses are shown.

Doses used in studies

These are doses tested in research, not personal advice. Some exceed the upper limit because they were short courses or given under medical care.

Strong evidenceStrong: meta-analyses of randomised trials or a large trial, with results that agree.Based on 1 meta-analysis, 2 reviews or position papers.How grades work

Muscle strength and high-intensity training (daily dose)

3-5 g a day

ISSN position stand: 3 to 5 g a day fills muscle stores over a few weeks. An optional loading phase (about 0.3 g per kg body weight a day for 5 to 7 days) fills them faster. Studies up to 30 g a day for 5 years found it safe in healthy people. A 2021 expert review of common questions gives the same daily range, or about 0.1 g per kg. A meta-analysis of 15 studies (497 people, 4 to 20 g a day, 5 days to over 2 years) found no kidney harm in healthy people.

Kreider RB et al. 2017 · Antonio J et al. 2021 · de Souza e Silva A et al. 2019

Strong evidenceStrong: meta-analyses of randomised trials or a large trial, with results that agree.Based on 1 review or position paper, 1 study.How grades work

Loading phase (first week only)

20 g a day, for a few days only

About 20 g a day, split into 4 doses of 5 g, for 5 to 7 days, then 3 to 5 g a day. It fills muscle stores in about a week instead of about 4. In 31 men, 20 g a day for 6 days and 3 g a day for 28 days ended at the same muscle creatine level, so loading is optional.

Kreider RB et al. 2017 · Hultman E et al. 1996

Strong evidenceStrong: meta-analyses of randomised trials or a large trial, with results that agree.Based on 2 reviews or position papers.How grades work

Daily dose by body weight

0.03-0.10 g per kg of body weight a day

Most studies used a maintenance dose of 2 to 5 g a day, which the NSCA gives as about 0.03 g per kg of body weight. A 2021 expert review gives about 0.1 g per kg a day as the higher option, the same as 3 to 5 g for most people.

NSCA 2019 · Antonio J et al. 2021

Strong evidenceStrong: meta-analyses of randomised trials or a large trial, with results that agree.Based on 2 reviews or position papers.How grades work

Loading phase by body weight (first week only)

0.30 g per kg of body weight a day, for a few days only

About 0.3 g per kg of body weight a day, split into 4 doses, for 5 to 7 days, then the daily dose. For a 70 kg person this is about 20 g a day.

Kreider RB et al. 2017 · NSCA 2019

Moderate evidenceModerate: smaller trials, mixed results or official guidance.Based on 1 meta-analysis.How grades work

Older adults doing strength training

3-5 g a day

Meta-analysis of 22 trials (721 people, average age 57 to 70) training 2 to 3 days a week for 7 to 52 weeks: creatine added about 1.4 kg more lean mass than training alone, and a small extra gain in chest press and leg press strength. Several trials started with a loading week of 20 g a day.

Chilibeck PD et al. 2017

Weak evidenceWeak: one small trial, pilot data or results that conflict.Based on 2 meta-analyses. 1 finding disagrees.How grades work

Memory and thinking (short-term studies)

5-20 g a day

Review of 6 small trials (281 people) using 5 to 20 g a day for days to weeks: short-term memory may improve, possibly more in older adults and vegetarians. A later meta-analysis of 8 trials found a small memory benefit overall, coming mostly from adults aged 66 to 76. The trials are small and differ a lot from each other.

Avgerinos KI et al. 2018 · Prokopidis K et al. 2023

Other findings

In younger people (11 to 31 years) the same meta-analysis found no memory effect at all.

Prokopidis K et al. 2023

Weak evidenceWeak: one small trial, pilot data or results that conflict.Based on 1 randomised trial.How grades work

Depression, added to an antidepressant

5 g a day

One trial in 52 women with depression who took escitalopram: adding 5 g creatine a day for 8 weeks improved symptom scores more than placebo, starting from week 2. More people stopped early in the creatine group (8 of 25 against 5 of 27). Only try this together with your doctor.

Lyoo IK et al. 2012

Best form and why

Best form

Creatine monohydrate

Why: Creatine monohydrate is used in almost all the research, is cheap and works. Micronised monohydrate just dissolves more easily.

Alternatives: Creatine HCl: an 8-week trial in 40 young adults (0.03 g per kg a day) found it worked, but gave no benefit over monohydrate. Buffered creatine (Kre-Alkalyn) was no better than monohydrate for muscle creatine, body composition or strength in a 28-day trial, and did not cause fewer side effects.

Kreider RB et al. 2017 · Eghbali E et al. 2024 · Jagim AR et al. 2012 · Jäger R et al. 2011

Forms and labels

  • Creatine monohydrate
  • Creatine HCl (hydrochloride)
  • Buffered creatine (Kre-Alkalyn)

Study doses are grams of creatine monohydrate (about 88% creatine). HCl is about 78% creatine by its formula, so 1 g HCl counts as about 0.89 g monohydrate. For buffered creatine PillMath counts the label amount as monohydrate.

Food sources

Red meat and fish contain small amounts (about 1 to 2 g per 500 g).

Interactions

People with kidney disease should ask a doctor first. Creatine can raise blood creatinine, a kidney test marker, without kidney harm: tell your doctor you take it.

Safety

Early weight gain is mostly water in muscle.

Pregnant, breastfeeding, on medication, or managing a health condition? Check with a doctor or pharmacist before starting a supplement.

Sources

  1. Review / position paper Kreider RB et al. (2017). ISSN position stand: safety and efficacy of creatine supplementation in exercise, sport, and medicine. J Int Soc Sports Nutr 14:18
  2. Review / position paper Antonio J et al. (2021). Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show?. J Int Soc Sports Nutr 18(1)
  3. Meta-analysis de Souza e Silva A et al. (2019). Effects of creatine supplementation on renal function: a systematic review and meta-analysis. J Ren Nutr 29(6):480-489
  4. Study Hultman E et al. (1996). Muscle creatine loading in men. J Appl Physiol 81(1):232-237
  5. Review / position paper NSCA (2019). Creatine (excerpt from NSCA's Guide to Sport and Exercise Nutrition). National Strength and Conditioning Association
  6. Meta-analysis Chilibeck PD et al. (2017). Effect of creatine supplementation during resistance training on lean tissue mass and muscular strength in older adults: a meta-analysis. Open Access J Sports Med 8:213-226
  7. Meta-analysis Avgerinos KI et al. (2018). Effects of creatine supplementation on cognitive function of healthy individuals: A systematic review of randomized controlled trials. Exp Gerontol
  8. Meta-analysis Prokopidis K et al. (2023). Effects of creatine supplementation on memory in healthy individuals: a systematic review and meta-analysis of randomized controlled trials. Nutr Rev
  9. Randomised trial Lyoo IK et al. (2012). A randomized, double-blind placebo-controlled trial of oral creatine monohydrate augmentation for enhanced response to a selective serotonin reuptake inhibitor in women with major depressive disorder. Am J Psychiatry 169(9):937-945
  10. Randomised trial Eghbali E et al. (2024). Supplementing with which form of creatine (hydrochloride or monohydrate) alongside resistance training can have more impacts on anabolic/catabolic hormones, strength and body composition?. Physiol Res 73:739-753
  11. Randomised trial Jagim AR et al. (2012). A buffered form of creatine does not promote greater changes in muscle creatine content, body composition, or training adaptations than creatine monohydrate. J Int Soc Sports Nutr 9:43
  12. Review / position paper Jäger R et al. (2011). Analysis of the efficacy, safety, and regulatory status of novel forms of creatine. Amino Acids 40:1369-1383

Values checked: November 12, 2026.

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