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Probiotics: how much to take

Probiotics are live bacteria or yeasts. Effects depend on the strain and the reason for taking them; amounts are given in billions of CFU (colony-forming units).

Calculator Official intake Study doses Best form Safety Sources

Adults 18+ only
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Official daily intake

This is not an essential nutrient, so there is no official daily intake. Only study doses are shown.

Doses used in studies

These are doses tested in research, not personal advice. Some exceed the upper limit because they were short courses or given under medical care.

Moderate evidenceModerate: smaller trials, mixed results or official guidance.Based on 2 meta-analyses.How grades work

Diarrhoea from antibiotics

No single dose

A Cochrane review of 39 studies (9,955 people) found probiotics during antibiotics cut C. difficile diarrhoea by about 60%, mainly in people at higher risk (over 5%). In children, diarrhoea from antibiotics fell from 19% to 8% (33 studies).

Goldenberg JZ et al. 2017 · Guo Q et al. 2019

Best form and why

No best form

Why: Results come from specific strains, such as Lactobacillus rhamnosus GG and Saccharomyces boulardii; check that your product names its strains.

Goldenberg JZ et al. 2017

Food sources

Yoghurt, kefir, sauerkraut and other fermented foods with live cultures.

Interactions

Take them a few hours apart from antibiotic doses.

Safety

People who are very ill or have a weak immune system should ask a doctor first.

Pregnant, breastfeeding, on medication, or managing a health condition? Check with a doctor or pharmacist before starting a supplement.

Sources

  1. Meta-analysis Goldenberg JZ et al. (2017). Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children. Cochrane Database Syst Rev 12:CD006095
  2. Meta-analysis Guo Q et al. (2019). Probiotics for the prevention of pediatric antibiotic-associated diarrhea. Cochrane Database Syst Rev 4:CD004827

Values checked: November 12, 2026.

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