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Selenium: how much to take

Selenium is part of antioxidant enzymes and thyroid hormone metabolism. Soil levels vary a lot by region.

Calculator Official intake Study doses Best form Safety Sources

Adults 18+ only
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Official daily intake

EFSA (European Food Safety Authority)

AI (adequate intake)

Men70 µg
Women70 µg
Pregnancy70 µg
Breastfeeding85 µg

Safe upper limit: 255 µg a day

Source: EFSA 2017 · EFSA 2025

NIH / NASEM (United States)

RDA (recommended dietary allowance)

Men55 µg
Women55 µg
Pregnancy60 µg
Breastfeeding70 µg

Safe upper limit: 400 µg a day

Source: National Academies (NASEM) 2019

Doses used in studies

These are doses tested in research, not personal advice. Some exceed the upper limit because they were short courses or given under medical care.

Strong evidenceStrong: meta-analyses of randomised trials or a large trial, with results that agree.Based on 1 randomised trial.How grades workNo benefit or harm found

Prevent prostate cancer

200 µg a day

SELECT gave healthy men 200 µg selenium a day. It did not lower prostate cancer.

Klein EA et al. 2011

Weak evidenceWeak: one small trial, pilot data or results that conflict.Based on 1 meta-analysis.How grades work

Hashimoto's thyroiditis (thyroid antibodies)

200 µg a day

Meta-analysis (Thyroid 2016): around 200 µg selenium a day for 3 to 12 months lowered thyroid peroxidase antibodies in people with Hashimoto's on thyroid hormone. It is not clear that this improves symptoms or thyroid function. Discuss with your doctor.

Wichman J et al. 2016

Best form and why

No clear winner

Label shows elemental amount (a good choice among equals)

Why: Selenomethionine, selenium yeast, sodium selenite and selenate are all absorbed well, up to about 90%. Labels give elemental selenium, which is what to compare.

Alternatives: Brazil nuts are very rich in selenium (68 to 91 µg per nut) and vary a lot, so regular large amounts can be too much.

NIH Office of Dietary Supplements 2026

Food sources

Brazil nuts (very high and variable), fish, eggs, meat.

Interactions

Count Brazil nuts: one nut can contain a lot of selenium.

Safety

Too much causes brittle hair and nails and a garlic breath odour. EFSA lowered its safe limit to 255 µg in 2023.

Pregnant, breastfeeding, on medication, or managing a health condition? Check with a doctor or pharmacist before starting a supplement.

Sources

  1. Official reference EFSA (2017). Dietary Reference Values for nutrients: Summary report. EFSA Supporting Publications
  2. Official reference EFSA (2025). Overview on Tolerable Upper Intake Levels as derived by the SCF and the EFSA NDA Panel (version 11, August 2025). EFSA
  3. Official reference National Academies (NASEM) (2019). Dietary Reference Intakes: RDA, AI and UL tables (via NIH ODS Nutrient Recommendations). Food and Nutrition Board
  4. Randomised trial Klein EA et al. (2011). Vitamin E and the Risk of Prostate Cancer: The Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA 306(14):1549-1556
  5. Meta-analysis Wichman J et al. (2016). Selenium Supplementation Significantly Reduces Thyroid Autoantibody Levels in Patients with Chronic Autoimmune Thyroiditis: A Systematic Review and Meta-Analysis. Thyroid
  6. Official reference NIH Office of Dietary Supplements (2026). Selenium: fact sheet for health professionals (checked November 2026). NIH ODS

Values checked: November 12, 2026.

Fact sheets on other sites

Independent summaries to read alongside this page. PillMath is not affiliated with these sites.

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