These are doses tested in research, not personal advice. Some exceed the upper limit because they were short courses or given under medical care.
Strong evidenceStrong: meta-analyses of randomised trials or a large trial, with results that agree.Based on 1 meta-analysis.How grades work
Shorter colds (taken every day, not only when sick)
200-2,000 mg a day
Cochrane review: taking at least 200 mg every day did not prevent colds in most people, but colds were about 8% shorter in adults and 14% shorter in children. Starting only after symptoms began showed no consistent effect.
Moderate evidenceModerate: smaller trials, mixed results or official guidance.Based on 1 randomised trial.How grades work
Slow age-related macular degeneration (as part of the AREDS formula)
500 mg a day
AREDS gave 500 mg vitamin C with vitamin E, beta-carotene, zinc and copper to people who already had intermediate macular degeneration. The full combination lowered the odds of advanced disease by about 28%. Vitamin C was never tested alone, and people without the disease were not shown to benefit.
These targets come from named organisations, not from EFSA or the NIH. They are listed so you can see the case for a higher intake, with the source behind each one.
Moderate evidenceModerate: smaller trials, mixed results or official guidance.Based on 1 official reference.How grades workMedical or scientific body
Linus Pauling Institute: Daily intake for adults
400 mg a day
The Linus Pauling Institute recommends at least 400 mg vitamin C a day for adult men and women, against the EFSA value of 110 mg for men and 95 mg for women. The institute was founded by Linus Pauling, who argued for high-dose vitamin C.
Why: Plain ascorbic acid is absorbed as well as vitamin C from food. In comparisons, Ester-C and ascorbic acid with bioflavonoids gave the same blood levels, so the NIH calls simple ascorbic acid the preferred source.
Alternatives: Buffered forms (sodium or calcium ascorbate) can be easier on a sensitive stomach.