Skip to content

Vitamin E: how much to take

Vitamin E is a fat-soluble antioxidant. Deficiency is rare in healthy adults.

Calculator Official intake Study doses Best form Safety Sources

Adults 18+ only
Loading calculator…

Official daily intake

EFSA (European Food Safety Authority)

AI (adequate intake)

Men13 mg
Women11 mg
Pregnancy11 mg
Breastfeeding11 mg

Safe upper limit: 300 mg a day

EFSA is reviewing this safe limit.

Source: EFSA NDA Panel 2015 · EFSA 2025

NIH / NASEM (United States)

RDA (recommended dietary allowance)

Men15 mg
Women15 mg
Pregnancy15 mg
Breastfeeding19 mg

Safe upper limit: 1,000 mg a day

Safe limit applies to any form of supplemental alpha-tocopherol.

Source: National Academies (NASEM) 2019

mg alpha-tocopherol.

Doses used in studies

These are doses tested in research, not personal advice. Some exceed the upper limit because they were short courses or given under medical care.

Strong evidenceStrong: meta-analyses of randomised trials or a large trial, with results that agree.Based on 1 randomised trial.How grades workNo benefit or harm found

Prevent prostate cancer

180 mg a day

SELECT gave 35,000 healthy men 400 IU synthetic vitamin E (about 180 mg) a day. Instead of preventing it, vitamin E alone raised prostate cancer risk by about 17%.

Klein EA et al. 2011

Moderate evidenceModerate: smaller trials, mixed results or official guidance.Based on 1 randomised trial.How grades work

Fatty liver disease with inflammation (NASH), without diabetes

536 mg a day

PIVENS: 800 IU natural vitamin E a day (about 536 mg) for 96 weeks improved liver biopsies in 43% of people vs 19% on placebo. This is a supervised treatment dose, well above the EFSA safe limit, for diagnosed NASH only.

Sanyal AJ et al. 2010

Best form and why

Best form

Natural (d-alpha-tocopherol)

Why: Natural vitamin E (d-alpha-tocopherol, RRR) is about twice as active per mg as the synthetic dl-form, so 1 IU natural is 0.67 mg and 1 IU synthetic is 0.45 mg.

Alternatives: For most people, food (oils, nuts, seeds) covers vitamin E; high-dose pills have shown harm in some trials.

NIH Office of Dietary Supplements 2026

Forms and labels

  • Natural (d-alpha-tocopherol)
  • Synthetic (dl-alpha-tocopherol)

Food sources

Vegetable oils (sunflower, wheat germ), nuts, seeds.

Interactions

High doses may add to bleeding risk with blood thinners.

Safety

IU depends on the form: 1 IU = 0.67 mg natural or 0.45 mg synthetic. Pick the form so the maths is right.

Pregnant, breastfeeding, on medication, or managing a health condition? Check with a doctor or pharmacist before starting a supplement.

Sources

  1. Official reference EFSA NDA Panel (2015). Scientific Opinion on Dietary Reference Values for vitamin E as alpha-tocopherol. EFSA Journal 13(7):4149
  2. Official reference EFSA (2025). Overview on Tolerable Upper Intake Levels as derived by the SCF and the EFSA NDA Panel (version 11, August 2025). EFSA
  3. Official reference National Academies (NASEM) (2019). Dietary Reference Intakes: RDA, AI and UL tables (via NIH ODS Nutrient Recommendations). Food and Nutrition Board
  4. Randomised trial Klein EA et al. (2011). Vitamin E and the Risk of Prostate Cancer: The Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA 306(14):1549-1556
  5. Randomised trial Sanyal AJ et al. (2010). Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis (PIVENS). N Engl J Med
  6. Official reference NIH Office of Dietary Supplements (2026). Vitamin E: fact sheet for health professionals (checked November 2026). NIH ODS

Values checked: November 12, 2026.

Fact sheets on other sites

Independent summaries to read alongside this page. PillMath is not affiliated with these sites.

Other supplements